HBV Plasmids

HBV plasmids are specialized genetic tools designed to study the hepatitis B virus (HBV), a major human pathogen responsible for chronic liver infections, cirrhosis, and hepatocellular carcinoma (HCC). These plasmids typically contain HBV genome fragments or the full-length HBV genome, enabling researchers to investigate HBV replication, transcription, protein expression, and interactions with host cells.

Key Features of HBV Plasmids
  • Full-Length HBV Genome:
    • Many HBV plasmids carry the entire viral genome (~3.2 kb), which is essential for studying the virus's replication and lifecycle.
  • HBV Promoters:
    • Includes HBV-specific promoters, such as the core, preS1, preS2, and X promoters, which regulate viral gene expression.
  • Replication Competence:
    • Replication-competent plasmids allow production of HBV DNA and proteins when transfected into suitable cells.
  • Selectable Markers:
    • Often include antibiotic resistance genes (e.g., ampicillin or kanamycin) for propagation in bacterial systems.
Applications of HBV Plasmids
  • HBV Replication Studies:
    • Investigate the HBV replication cycle, including transcription, translation, and reverse transcription.
  • Gene Function Analysis:
    • Study the role of individual HBV genes (e.g., S, C, P, X) in viral pathogenesis and host interactions.
  • Antiviral Drug Development:
    • Screen potential antiviral compounds targeting HBV replication or specific viral proteins.
  • Immunology Research:
    • Explore immune responses to HBV antigens (e.g., HBsAg, HBcAg) in vitro or in vivo.
  • HBV-Host Interaction:
    • Investigate interactions between HBV proteins and host factors that regulate infection and immune evasion.
  • Vaccine Development:
    • Express HBV antigens (e.g., HBsAg) for subunit vaccine research.

HBV plasmids are indispensable tools for studying the biology of hepatitis B virus and its impact on host cells. Their versatility enables applications in basic research, drug discovery, immunology, and vaccine development.

AffiPLASMID® pML-T7-6×His-HBV-X (virus) -6×His
CAT# AFG-NVF-105170
Size: 2 μg
486.00 486.0 USD
AffiPLASMID® pML-T7-6×His-HBV-S (virus) -6×His
CAT# AFG-NVF-105169
Size: 2 μg
486.00 486.0 USD
486.00 486.0 USD
486.00 486.0 USD
AffiPLASMID® pmCherry-3XLinker-HBV-S
CAT# AFG-NVF-104769
Size: 2 μg
486.00 486.0 USD
AffiPLASMID® pmCherry-3XLinker-HBV-PreS2
CAT# AFG-NVF-104768
Size: 2 μg
486.00 486.0 USD
AffiPLASMID® pmCherry-3XLinker-HBV-PreS1
CAT# AFG-NVF-104767
Size: 2 μg
486.00 486.0 USD
AffiPLASMID® pmCherry-3XLinker-HBV-P
CAT# AFG-NVF-104766
Size: 2 μg
486.00 486.0 USD
AffiPLASMID® pHBV-Luc
CAT# AFG-NVF-100749
Size: 2 μg
486.00 486.0 USD
486.00 486.0 USD
AffiPLASMID® pEnCMV-FLAG-HBV-X-SV40-Neo Plasmid
CAT# AFG-NVF-093918
Size: 2 μg
486.00 486.0 USD
AffiPLASMID® pEnCMV-FLAG-HBV-S-SV40-Neo Plasmid
CAT# AFG-NVF-093917
Size: 2 μg
486.00 486.0 USD
AffiPLASMID® pEnCMV-FLAG-HBV-P-SV40-Neo Plasmid
CAT# AFG-NVF-093916
Size: 2 μg
486.00 486.0 USD
486.00 486.0 USD
AffiPLASMID® pCMV-FLAG-HBV-C-SV40-Neo Plasmid
CAT# AFG-NVF-078221
Size: 2 μg
486.00 486.0 USD
AffiPLASMID® 1.3xWT HBV-Luciferase Plasmid
CAT# AFG-NVF-000002
Size: 2 μg
486.00 486.0 USD